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The influence of the Protecto-active probiotic on the content of biotic elements in blood serum of piglets
The modern pig production technology involves the concentration of the large numbers of animals in restricted areas, the use of antibiotics and other antimicrobial drugs. They leads to the development of mass dysbacteriosis, disorders of digestive functions, nutrient deficiencies, especially protein, as well as amino acids, vitamins, macro- and microelements. It also causes a decrease in increments, an increase in fattening terms, overage of feed and, consequently, an increase in the cost price of pork.
In recent years, in Ukraine and in many countries of the world, probiotics, which are the catalysts of metabolic processes in the body, have been procured for the prevention and treatment of digestive disorders. Probiotics normalize the processes of digestion due to the correction of qualitative and quantitative composition of the microflora of the gastrointestinal tract, contributing to increasing the natural resistance of the animals organism.
The period of weaning in pig breeding is one of the most important, since that time the piglets are switching to another type of feeding, they begin to come in contact with other pigs in a new environment that is accompanied by stress, a decrease in the natural resistance and immunological reactivity of the organism. The damage of the normal microflora structure of the gastrointestinal tract. As a result of which gastrointestinal disorders arise, daily average gains decrease and mortality increases.
The main purpose of the use of probiotics is the formation of a metabolic active population of probiotic bacteria in the digestive tract, which contributes to a qualitative change in the composition of the intestinal flora and the displacement of pathogenic microorganisms, and also an increase in the bacterial synthesis of enzymes and throughput of the intestinal mucosa.
When using probiotic drugs in livestock production, the quality of feed use is increased, animal growth and productivity are accelerated, as well as the cost of production and the number of cases of morbidity and mortality among young animals are reduced.
The purpose of our work was to study the effect of Protecto active probiotic on the macro and microelements in piglets blood serum during the period of weaning from the sow.
For the experiment there were taken piglets of 45 days of age, taking into account the breed, live weight and total physiological state. The conditions for keeping and feeding animals were the same. For pigs in the experimental group, in addition to the main diet, the Protecto active probiotic was administered at a dose of 2 g per 10 kg of body weight, which was given together with the food 1 time per day for 30 days.
To determine the effect of Protecto active on the biotic elements of animals blood serum of all groups, blood was collected from the orbital sinus, in the morning, before feeding. Blood tests were conducted before feeding probiotics, as well as at 30, 45, and 60 from the beginning of experiment.
Mineral elements in the body of animals play an important role, so studying the effects of feed additives on their content and assimilation is an important stage in the research. After all, it is micro and macro elements that are an important factor in increasing the natural resistance of the organism of young animals.
As a result of the use of Protecto active probiotic there have been established, some positive effects on the macro and microelements of piglets blood serum during the period of weaning from the sow. An increase in total calcium content by 8.81 %, inorganic phosphorus by 5.85 %, magnesium by 12.80 %, ferrum by 6.95 %, copper by 2.90 %, zinc by 3.64 % was noted among experimental animals compared with a control group. Feeding the pigs with the Protecto active did not have a negative impact on the biotic parameters of the blood, all changes occurred within the physiological norm, among animals of the experimental group, there was an improvement in the physiological state, increased gain and livestock survival. It should be noted that all changes in the indexes of the content of macro- and microelements of the serum did not have a reliable nature and occurred within the limits of the physiological norm.
Key words: probiotic drugs, young pigs, average daily gain, metabolism, biochemical parameters, blood composition, prophylaxis, gastrointestinal tract.
https://orcid.org/0000-0003-3751-91401. Bolohovs'ka, V.A. (2010). Zastosuvannja probiotyka Protekto-aktyv pid chas vyroshhuvannja molodnjaku svynej [Application of probiotic Protective agent during growth of young pigs]. Bila Tserkva, 48 p.
2. Skybic'kyj, V.G., Kozlovs'ka, G.V. Probiotyky – efektyvnyj zasib profilaktyky zahvorjuvan' tvaryn. Naukovi praci Poltavs'koi' derzhavnoi' agrarnoi' akademii'. Serija: veterynarna medycyna [Probiotics – an effective means of preventing animal diseases. Scientific works of the Poltava State Agrarian Academy. Series: Veterinary Medicine], 2015, Ukrainian Scientific and Practical Conference "Current Issues and Recent Developments in the Problem of Infectious Pathology", Issue 9, pp. 32–34.
3. Voloshhuk, V. M. Stan i perspektyvy rozvytku galuzi svynarstva [Status and prospects of the pig industry], 2014, Bulletin of Agrarian Science, Vol. 2, pp. 17–20.
4. Bogdan, I.M., Pivtorak, Ja.I., Paranjak, R.P. Produktyvna dija kormovoi' dobavky “PROPIGplv” u racionah remont-nogo molodnjaku svynej [Productive action of the feed supplement "PROPIgplv" in the rations of repair young pigs]. Naukovyj visnyk L'vivs'kogo nacional'nogo universytetu veterynarnoi' medycyny ta bioteh-nologij im. S.Z. G'zhyc'kogo [Scientific herald of the Lviv National University of Veterinary Medicine and Biotechnology named after. S.Z. G'zhyc'kogo]. Lviv, Vol. 18, no. 1(65), 2016, part 3, pp. 8–9.
5. Panyn, A.N., Sovetkyn, S.V., Judyn, V.S. Jeffektyvnost' prymenenyja nekotoryh byologychesky aktyvnyh so-edynenyj v svynovodstveju Vestnyk Rossyjskoj akademyy sel'skohozjajstvennyh nauk [Efficiency of application of some biologically active compounds in pig breeding Bulletin of the Russian Academy of Agricultural Sciences], 2013, no. 4, pp. 45–46.
6. Blyznecov, A.V., Tokarev, Y.N., Fysenko, N.V. Yspol'zovanye probyotykov Vetosporyn y Vetosporyn-aktyv na dorashhyvanyy v uslovyjah promyshlennoj tehnology [The use of probiotics Vetosporin and Vetosporin-active in rearing under the conditions of industrial technology]. Sovremennye dostizhenija veterinarnoj mediciny i biologii – v sel'skohozjajstvennoe proizvodstvo: materialy II Vseross. nauch.-prakt. konf. s mezhdunar. uchastiem, posv. 100-letiju prof. Ajupova H.V.
21-22 fevralja 2014 g [Modern advances in veterinary medicine and biology – in agricultural production: materials II Russ. scientific-practical conf. from Intern. participation dedicated 100th anniversary of prof. Ayupova Kh.V. February 21-22, 2014]. Ufa, Bashkyrskyj GAU, 2014, pp. 318–320.
7. Pavlova, M.V., Alekseev, Y.A. Kormovye dobavky «Bacell», «Larykarvyt» y yh vlyjanye na belkovyj obmen y produktyvnost' porosjat [Feed additives "Bacell", "Laricarvit" and their effect on protein metabolism and piglet productivity], 2013, Veterinarian, no. 2, pp. 54–57.
8. Chernjavs'kyj, O.O. Efektyvnist' vykorystannja v godivli svynej probiotyku u pojednanni z fermentnym prepa-ratom [Effectiveness of the virus in the year of the pig probiotics in supplementary enzyme preparations]. Tehnologija vyrobnyctva i pererobky produkcii' tvarynnyctva: zb. nauk. prac' [Collected works of Animal Husbandry Products Production and Processing]. Bila Tserkva, 2015, no. 2, pp. 171–173.
9. Nekrasov, R.V., Chabaev, M.G., Bobrovskaja, O.Y. Probyotyky v kormlenyy porosjat [Probiotics in feeding pigs]. Svynovodstvo [Pig breeding], 2013, no. 6, pp. 31–33.
10. Hardy, H., Harris, J., Lyon, E., Beal, J., Foey, A.D. Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology Nutrients. 2013, no. 5, pp. 1869–1912.
11. Campbell, J.M., Crenshaw, J.D., Polo, J. The biological stress of early weaned piglets. J Anim Sci Biotechnol. 2013, no. 4, 19 p.
12. Yang, F., Hou, C., Zeng, X., Qiao, S. The use of lactic acid bacteria as a probiotic in swine diets. Pathogens. 2015, no. 4, pp. 34–45.
13. Heo, J.M., Opapeju, F.O., Pluske, J.R., Kim, J.C., Hampson, D.J., Nyachoti, C.M. Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobials.
J Anim Physiol Anim Nutr. 2013, no. 97, pp. 207–237.
14. Moshkutelo, Y., Ygrat'eva, L., Tokar', V. Probyotyk dlja svynomatok y porosjat [Probiotic for sows and piglets]. Kombykorma [Fodder], 2013, no. 97, pp. 207–237.
15. Kozlovs'ka, G.V., Skybic'kyj, V.G. Kontrol' mikroflory biotypiv tvarynnogo organizmu – vazhlyvyj element v organizacii' otrymannja jakisnoi' j bezpechnoi' produkcii' [The control of biocotypes of the organisms is an important element in organizing the organization of leisureless products]. Visnyk Poltavs'koi' agrarnoi' derzhavnoi' akademii' [Bulletin of the Poltava Agrarian State Academy], 2013, no. 4, pp. 56–58.
16. Mashkin, Ju.O., Karkach, P.M. Zberezhenist' i produktyvnist' kurchat- brojleriv u razi zastosuvannja probiotyka «Protekto- Aktyv» [Save and produce kurchat-broilers at the same time as Protetik-Aktivi probiotics], 2008, Bila Tserkva Scientific Bulletin, pp. 345–351.
17. Mel'nychenko, Ju.O., Bitjuc'kyj, V.S. Sklad mikroflory kyshechnyku kurchat-brojleriv za zastosuvannja poli-funkcionalnyh probiotykiv [Composition of intestinal microflora of chicken broilers for the use of multifunctional probiotics]. Tehnologija vyrobnyctva i pererobky produkcii' tvarynnyctva: zb. nauk. prac'. Bila Cerkva [Collected works of Animal Husbandry Products Production and Processing]. Bila Tserkva, 2015, no. 2, pp. 29–32.
18. Mel'nychenko, Ju.O. Vplyv probiotychnyh preparativ na biohimichni pokaznyky krovi kurchat-brojleriv [Influence of probiotic drugs on the biochemical parameters of blood of broiler chickens]. Tehnologija vyrobnyctva i pererobky produkcii' tvarynnyctva: zb. nauk. prac'. [Collected works of Animal Husbandry Products Production and Processing]. Bila Tserkva, 2015, no. 1 (116), pp. 180–183.
19. Mel'nychenko, Ju.O., Bitjuc'kyj, V.S. Metodychni rekomendacii' shhodo zastosuvannja probiotykiv za vyroshhuvannja kurej-brojleriv [Methodical recommendations on the use of probiotics for the cultivation of broiler chickens]. Bila Tserkva, 2015, 16 p.
20. Fouhse, J.M., Zijlstra, R.T., Willing, B.P. The role of gut microbiota in the health and disease of pigs. Anim Front. 2016, no. 6, pp. 30–36.
21. Hou, C., Zeng, X., Yang, F., Liu, H., Qiao, S. Study and use of the probiotic Lactobacillus reuteri in pigs: a review. J Anim Sci Biotechnol. 2015, no. 6, 14 p.
22. Kim, H.B., Isaacson, R.E. The pig gut microbial diversity: understanding the pig gut microbial ecology through the next generation high throughput sequencing. Vet Microbiol. 2015, no. 177, pp. 242–251.
23. Ahasan, A.S., Agazzi, A., Invernizzi, G., Bontempo, V., Savoini, G. The beneficial role of probiotics in monogastric animal nutrition and health. J Dairy Vet Anim Res. 2015, no. 2, 41 p.
24. Cai, L., Indrakumar, S., Kiarie, E., Kim, I.H. Effects of a multi-strain Bacillus species-based direct-fed microbial on growth performance, nutrient digestibility, blood profile, and gut health in nursery pigs fed corn-soybean meal-based diets. J Anim Sci. 2015, no. 93, pp. 4336–4342.
25. Pamer, E.G. Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogens. Science. 2016, no. 352, pp. 535–538.
26. Upadhaya, S.D., Kim, S.C., Valientes, R.A., Kim, I.H. The effect of Bacillus-based feed additive on growth performance, nutrient digestibility, fecal gas emission, and pen cleanup characteristics of growing-finishing pigs. Asian Australas J Anim Sci. 2015, no. 28, pp. 999–1005.
27. Yirga, H. The use of probiotics in animal nutrition. J Prob Health. 2015, no. 3, 132 p.
28. Mironov, A. Vybor kormov dlja porosjat-ot#emyshej [Choice of feed for weaned piglets]. Zhivotnovodstvo Rossii [Russian animal husbandry], 2014, no. 2, pp. 20–22.
29. Thacker, P.A. Alternatives to antibiotics as growth promoters for use in swine production: a review. J Anim Sci Biotechnol. 2013, no. 4, 35 p.
30. Labinov, V.V. Rezervy dlja rosta ob#emov svininy [Reserves for pork growth]. Zhivotnovodstvo Rossii [Russian animal husbandry], 2014, no. 1, pp. 4–5.
31. Sezen, A.G. Effects of prebiotics, probiotics and synbiotics upon human and animal health. Atatürk Üniv Vet Bil Dergm. 2013, no. 8, pp. 248–258.
32. Doron S., Snydman D.R. Risk and safety of probiotics. Clin Infect Dis. 2015, no. 60 (Suppl. 2), pp. 129–134.
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