A research study was conducted to find the effect aqueous extract mixture of Zingiberofficinale, Carumcapticum, Withania somnifera, Trigonella foenum graecum, Silybummarianum, Allium sativum and Berberis lyceum on the growth performance of internal organs, lipid profile and hepatotoxicity of broiler chicks. A total of 240 day old chicks were purchased and were reared for 35 days in summer month. The birds were raised on conventional deep litter system, in open shed and all the pens/cages were placed in the same shed to ensure the same environment for all of the groups. Each pen was provided with a feeder and drinker. This aqueous extract mixture of plant was then mixed in drinking water of chicks at the rate of @ 0.0, 5.0, 10.0 and 15.0 ml/L for group A, B, C and D, respectively while group A served as a control. Feed and water were provided on calculated basis. Total numbers of chicks were divided into four groups (A, B, C and D) each having 60 chicks. Each group was further subdivided into three groups (replicates) each having 20 chicks. The data were recorded to explore the effect of infusion based plant mixture on the lipid profile and hepatotoxicity. AST and ALP had significantly (P<0.05) decreasing trend in groups B, C & D. ALT was significantly (P<0.05) lower in Group B. Group D had significantly (P<0.05) lower cholesterol, Triglyceride and LDL and higher HDL values. Serum protein were significantly (P<0.05) higher in group A. Group B @ 5.0 ml/L of Aqueous Extract water to improve liver function. Lipid profile could be well controlled, while using plant mixture extract @ 15.0 ml/L of water. Therefore the use of these medicinal plants is of great concern especially for broiler hepatic-toxicity and lipid profile.

Keywords: Broilers, lipid profile, hepatotoxicity, higher density lipoprotein.