In the context of the modern industrialisation of poultry farming and the growing global demand for quail products, fnding effective ways to improve bird productivity and health is extremely important. One of the most promising approaches is the use of nanoselenium bio-compounds with probiotics to improve the metabolic parameters of quail. Recent research has focused on the synthesis of selenium nanoparticles using probiotics as an environmentally friendly alternative to traditional methods of adding inorganic selenium to quail feed. The advantage of this approach is the production of a biocompatible and bioavailable form of selenium, which provides birds with the ability to effectively absorb and use selenium for various physiological processes. The effect of innovative feed additives, such as selenium nanoconjugates and probiotics, on various metabolic parameters in quail was investigated. These include the activity of antioxidant defence enzymes, indicators of carbonyl oxidative stress, protein carbonyl levels and protein metabolism. By adding selenium nanoconjugates and probiotics to quail feed, an improvement in antioxidant defence mechanisms was observed, leading to a reduction in oxidative stress and an improvement in the overall health of the birds. In addition, improved protein metabolism as a result of these supplements has been shown to have a positive impact on the productivity and quality of quail products. In summary, investing in high quality feed additives such as selenium nanoconjugates and probiotics is a strategic approach to improving the productivity and proftability of poultry production. By taking advantage of the benefts of nanotechnology and probiotics, farmers can optimise the health and productivity of their poultry flocks, meeting the growing demand for quail products on the national market.

Key words: bionanotechnology, nanoselenium conjugates, biogenic synthesis, quercetin, quail, blood, liver, biochemical parameters, oxidative modifcation of proteins.